The efficacy and safety of cardio-protective therapy in patients with 5-FU (Fluorouracil)-associated coronary vasospasm.
BackgroundCoronary vasospasm is a known side effect of 5-FU (fluorouracil) therapy.Beyond switching to non-5FU-based chemotherapy, there are no established treatments for 5-FU associated coronary vasospam.Our objective was to assess the safety and efficacy of re-challenge with 5-FU after pre-treatment with calcium channel blockers (CCBs) and long-a